THROUGH THE LOOKING GLASS: VISUALIZING LEUKEMIA GROWTH, MIGRATION, AND ENGRAFTMENT USING FLUORESCENT TRANSGENIC ZEBRAFISH

Through the Looking Glass: Visualizing Leukemia Growth, Migration, and Engraftment Using Fluorescent Transgenic Zebrafish

Zebrafish have emerged as a powerful model of development and cancer.Human, mouse, and zebrafish malignancies exhibit striking histopathologic and molecular similarities, underscoring the remarkable conservation of genetic pathways required to induce cancer.Zebrafish are uniquely hydrangea red sensation suited for large-scale studies in which hundr

read more


Therapeutic Antibody-Like Immunoconjugates against Tissue Factor with the Potential to Treat Angiogenesis-Dependent as Well as Macrophage-Associated Human Diseases

Accumulating evidence suggests that tissue factor (TF) is selectively expressed in pathological angiogenesis-dependent as well as macrophage-associated human diseases.Pathological angiogenesis, the formation of neovasculature, is involved in many clinically significant human diseases, notably cancer, age-related macular degeneration (AMD), endometr

read more